Richard Baybutt, Ph.D.

Applied Health Science

Professor of Applied Health Science, Department Chair
On Faculty since 2007

Email:

Education

Postdoctoral Fellow, Division of Pharmacology and Experimental Therapeutics, Univ. of  Kentucky, 1992-1994
Mentor: Mark Gillespie, PhD, Professor and Chair

Ph.D. Nutrition, The Penn State University, 1992

M.S. Nutrition, Maryland University, 1983

B.S. Psychology, Syracuse University, 1978

About Richard Baybutt

Dr.  Richard Baybutt is Professor and Chair of the Applied Health Science Department at Wheaton College.  He is both internationally and nationally recognized in the field of nutrition science.  His research expertise is in the field of Nutrition and Toxicology where he has published in such prestigious journals as Journal of Biological Chemistry, Toxicology, Lipids, Current Pharmaceutical Design, and the Journal of Nutrition.  He has presented his research at such noteworthy colloquiums as the International Colloquium on Lung and Airway Fibrosis. He has served six times as a panel member of the USDA study section to review competitive grant proposals.  While serving as a faculty member at Kansas State University, he was awarded the Dawley-Scholar Award for Faculty Excellence in Student Development because of his research work with undergraduates, as well as his mentoring of graduate students.  Dr. Baybutt presently focuses on strengthening the growing research program of the Applied Health Science department with its emphasis on pre-professional preparation and training for prestigious graduate programs throughout the country.  Dr. Baybutt brings over 30 years of teaching experience to Wheaton College in the field of nutrition, and joins Wheaton College’s mission to give the students highly qualified training in research and publishing, as well as the finest academic instruction in nutrition science and nutrition related fields. 

Curriculum Vitae (PDF)

Professional Appointments

  • Professor and Chair, Applied Health Science Department, Wheaton College, 2008-Present
  • Professor, Applied Health Science Department, Wheaton College, 2007
  • Associate Professor,* Department of Human Nutrition, Kansas State University, 2000-2007
  • Assistant Professor,* Department of Human Nutrition, KSU, 1994-2000
  • Instructor, Department of Nutrition and Food Science, Univ. of Kentucky, 1994 (during my postdoctoral fellowship)

  • *Graduate Faculty Status in the Human Nutrition Department and in the Interdepartmental Biochemistry Group and the Kinesiology Dept. at KSU. 

Administrative Appointments

  • Chair, Applied Health Science Department, Wheaton College, Wheaton, IL, 2008-Present
  • Chair, Institutional Animal Care and Use Committee, Wheaton College, 2011
  • Chair, Provost’s Office, The Big Twelve Faculty Fellowship Selection Committee, 2004
  • Chair, Faculty Council, College of Human Ecology, 2001-2002
  • Chair, College Committee on Planning (CCOP), 2001-2002
  • Chair, Nutrition and Exercise Faculty Search Committee, 2000
  • Chair, Building Space Committee, Dept. of Foods and Nutr., 1995-1998
  • Chair, Extension Search Committee, 1998 

International Presentations

  • Harris, E., Andres, E., Jang, A., Petrie, A., Doo, C., Safavi, S., Herndon, B., Vanden Heuvel, G., Molteni, A., and Baybutt, R.C. Pathological and Fibrotic Changes in the Lung of Cux-1 Transgenic Mice, Mont Tremblant, Quebec, Canada, Sept 20-24, 2014.
  • Molteni, A., Saettele, T., Herndon, B., Baybutt, R.C., and Standard, J. Vitamin A Deficiency and Effect on Pulmonary Fibrosis in Rats: Reversal of Effects by Retinoic Acid. 17th International Colloquium on Lung and Airway Fibrosis, Modena, Italy, Sept 29 – Oct 3, 2012.
  • Lawrenz J., Standard J., Nitz J., Kamal A., Mehrer A., Dim D., Herndon B., Rawls J., Molteni A. Flaxseed Oil Protection from Bleomycin-Induced Lung Vascular Damage:  A Rat Model, 16th International Colloquium on Lung and Airway Fibrosis, Busselton, Western Australia, Australia, October 30 - November 3, 2010.
  • Baybutt, R.C., Choi, S., Ransom, B., Herndon, B., Shaffley, S., Malburg, I., Kamal, A. Brennan, C., and Molteni, A. Protection from Bleomycin-Induced Fibrotic Damage in Rats by Flaxseed Oil Administration, 15th International Colloquium on Lung and Airway Fibrosis, Sunset Beach, North Carolina, September 28-October 4, 2008.
  • Baybutt, R.C., Bruening, C., Quinn, T. Herndon, B., and Molteni, A. Dietary Fatty Acids as Adjuvants in Healing Bleomycin-Induced Fibrosis, 14th International Colloquium on Lung and Airway Fibrosis, Eltville, Germany, September 7-10, 2006.
  • Molteni, A., van Dillen, C, Herndon, B., Quinn, T. Lindshield, B.,and Baybutt, R.C.  Role of  Retinoic Acid in the Pathogenesis of Cigarette Smoke-Induced Emphysema in the Rat, 13th International Colloquium on Lung and Airway Fibrosis, Banff, Canada, October 17-20, 2004.
  • Baybutt, R.C., Herndon, B., Latcham, S., Li, T. and Molteni, A.  Effects of Retinoic Acid and Captopril on a Lung Fibrosis Model, 12th International Colloquium on Lung and Airway Fibrosis, Glion, Switzerland, October 6-9, 2002.
  • Baybutt, R.C., Latkowvich, P., Li, T., Rosales, C., Brady, H., and Molteni, A.  Drugs, nutrients and their interaction in attenuating lung pathologies induced by monocrotoline.  Lovelace Respiratory Research Institute International Symposium:  Remodeling and Repair in Respiratory Diseases, Santa Fe, New Mexico, October 15-17, 2001.
  • Baybutt, R.C., Rosales, C., Kobbermann, S., Li, T., Veno, P. and Molteni, A.  Antioxidants vs angiotensin converting enzyme inhibitors protective effect in the monocrotaline induced model of experimental fibrosis in rats.  11th International Colloquium on Lung and Airway Fibrosis, Stockholm, Sweden, September 23-26, 2000.

Membership in Professional Societies

  • American Society for Nutrition
  • American Society for Nutritional Sciences: A constituent society of the Federation of American Societies for Experimental Biology  
  • Societies for Experimental Biology
  • Gamma Sigma Delta
  • Sigma Xi Honor Society
  • Omicron Nu Honor Society

 Reviewer for Grants and Manuscripts

  • Panel Member for the USDA (National Research Initiative Competitive Grants Program),
    2002, 2003, 2005, 2006, 2011.
  • Editorial Board for Frontiers in Nutrigenomics, 2011-present.
  • Ad Hoc Reviewer for the American Diabetes Association, 2004, 2005, 2006.
  • Clinical and Applied Immunology Review
  • European Journal of Clinical Nutrition
  • European Respiratory Journal
  • Experimental Parasitology
  • Journal of the American College of Nutrition
  • Journal of Applied Physiology
  • Journal of Nutrition
  • Journal of Nutritional Biochemistry
  • McGraw-Hill Publishing Company
  • Respiratory Research
  • Steroids
  • Toxicology
  • Proceedings of the American Society of Experimental Biology and Medicine
  • Research Excellence Committee for Sigma Xi to select the Master’s Thesis of the year
    Sarah Morrison Grant Competition, School of Medicine, Univ. of Missouri-Kansas City, KS.
  • School Food Service Research Review (Published book review in vol. 20, p 37, 1996)
  • Wadsworth Publishing Company
  • World Book Publishing (The World Book Encyclopedia)  

Courses Taught

  • AHS 101 - Wellness
  • AHS 271 - Research Methods and Statistics
  • AHS 368 - Concepts in Nutrition
  • AHS 400 - Nutrition and Disease
  • AHS 468 - Advanced Nutrition: Vitamins 
  • AHS 495 - Independent Research -- Omega-3 Fatty Acids and Fibrosis   

Research

Research Interests

  • Omega-3 Fatty Acids and Prevention of Pulmonary Fibrosis
  • Retinoic Acid (vitamin A) and prevention of Emphysema

Extramural Funding Received

  • Department of Health and Human Services (National Institute of Health/National Cancer Institute), 2004-2007. Weight control, cell signaling and cancer prevention.
  • US Department of Agriculture (National Research Initiative Competitive Grants Program), 1999-2004. Role of vitaming A in lung epithelial cell repair.

Publications

Standard, J., Kunz, K., Dim, D, Quinn, T., Hamdan, H., Herndon, B., Zia, H., Mansour, A., Lankachandra, M., Molteni, A., and Baybutt, R.C. Vitamin A deficiency-induced aberrant bone pathology restored by retinoic acid but not by retinol in cod liver oil. Completed to be submitted to Journal of Biomedical Science, 2015.

Smith, V.L.B., Belfi, E., and Baybutt, R.C. Monocrotaline alters vitamin A and vitamin E concentrations in lung and liver of rats. Completed to be submitted to Journal of Nutrition and Food Sciences for 2014.

Xue, Y., Harris, E., Wang, W., and Baybutt, R.C. Vitamin A depletion induced by cigarette smoke is associated with an increase in lung cancer-related molecular markers in rats. Journal of Biomedical Science, accepted, 2014.

Standard, J., Jiang, Y., Yu, M., Su, X., Zhao, Z., Xu, J., Chen, J., King, B., Lu, L., Tomich, J., Baybutt, R., and Wang, W. Reduced signaling of PI3K-Akt and RAS-MAPK is the key target for weight-loss-induced cancer prevention by dietary calorie restriction and/or physical activity. Nutritional Biochemistry, in press, 2014.

Thomas, R., Meadors, E., Pilgrim, C., Johnson, H., Smith, M., Ianuzzo, C.D., and Baybutt, R.C. Two weeks of low dose fish oil supplementation followed by a single bout of exercise increases high density lipoprotein cholesterol in college-aged and middle-aged men. Journal of Nutrition and Food Sciences 3(5): 1-6, 2013.

Lawrenz, J.M, Herdon, B., Kamal, A., Mehrer, A., Dim, .D.C., Gasper, D, Nitz, J, Molteni, A., and Baybutt, R.C. Dietary flaxseed oil protects against bleomycin-induced pulmonary fibrosis. Pulmonary Medicine 2012:1-11, 2012.

Xue, Y., Meadors, E.P., Wang, W., Baybutt, R.C. Microarray Analysis Reveals that Dietary Retinoic Acid may Suppress Cancer-Related Gene Expression of  the Lungs of Cigarette-Smoked Rats. Journal of Nutrition and Food Sciences S2:1-6, 2012

Xue, Y., Haub, M.D., Smith, B.W., and Baybutt, R.C. Decreases in bone mineral content by dietary all-trans retinoic acid precede decreases in bone mineral density in a weanling rat model of cigarette smoke-induced lung injuries. International Journal for Vitamin and Nutrition Research. 81 (1): 5-11, 2011.

Baybutt, R.C.,  Smith, B.W., Donskaya, E.V., Hu, L., Li, T., and Wang, W.  The proliferative effects of retinoic acid on primary cultures of adult rat type II pneumocytes depend upon cell density1,2  In Vitro Cellular & Developmental Biology, 46: 20-27, 2010.      

Weeden AM, Remig VM, Holcomb CA, Herald TJ, and Baybutt RC.   Vitamin and mineral supplementation have a nutritionally significant impact on the micronutrient intakes of older adults attending senior centers.  Journal of Nutrition for the Elderly 29 (2):241-254, 2010.

Xie, L., Jiang, Y., Ouyang, P., Chen, J., Doan, H., Herndon, B., Sylvester, J., Zhang, K., Molteni, A., Reichle, M., Zhang, R., Haub, M.D., Baybutt, R.C. & Wang, W. Effects of dietary calorie restriction or exercise on the PI3K and Ras signaling pathways in the skin of mice. Journal of Biological Chemistry, 282: 28025-28035, 2007

Baybutt, R.C. & Molteni, A. Vitamin A and emphysema. Vitamins and Hormones, 75: 385-401, 2007

Lu, J., Xie, L., Sylvester, J., Wang, J., Bai, J., Baybutt, R.C. & Wang, W. Different gene expression of skin tissues between mice with weight controlled by either calorie restriction or physical exercise. Experimental Biology and Medicine, 232: 473-480, 2007.

Baybutt, R.C., Herndon, B.L., Umbehr, J., Mein, J., Xue, Y., Reppert, S., vanDillen, C., Halder, A. and Molteni, A. Effects of cytokines and histology by treatment with the ACE inhibitor captopril and the antioxidant retinoic acid in teh monocrotaline model of experimentally induced lung fibrosis. Current Pharmaceutical Design, 2007.

Lu, J., Xie, L., Sylvester, J., Wang, J., Baybutt, R.C. and Wang, W. Different gene expression in weight control mice between calorie restriction and physical exercise. Experimental Biology and Medicine, 232:473-480, 2007.

Xue, Y., Williams, T., Li, T., Umbehr, J., Fang, L., Wang, W., and Baybutt, R.C. Type III pneumoytes modulate surfactant production in response to cigarette smoke constituents: restoration by vitamin A and E. Toxicology In Vitro, 19: 1061-1069, 2005.

Qu, H., Madl, R.L., Takemoto, D.J., Baybutt, R.C., and Wang, W. Phytochemical lignans associated with cancer prevention by wheat bran: anti-cancer characteristics in colon cancer SW480 cells. Journal of Nutrition, 135: 598-602, 2005.

Kamal, R., Molteni, A., Zoubine, M., Norkin, M., Reppert, S., Xue, Y., Baybutt, R.C., Herndon, B. & Shnyra, A. Diet high in retinoic acid controls M1/M2 acivation phenotypes in macrophages and protects from monocrotaline-induced pulmonary fibrosis. Nutrition Research, 24: 773-785, 2004.

Molteni, A., Herndon, B., Kamal, A., Castellani, W., Reppert, S., Xue, Y., Umbehr, J. & Baybutt, R.C. Effects of the antioxidant alpha-tocopherol in an experimental model of pulmonary hypertension and fibrosis: administration of monocrotaline. Nutrition Research, 24: 707-720, 2004.

Li, T., Molteni, A., Latkovich, P., Castellani, W., & Baybutt, R.C. Vitamin A depletion induced by cigarette smoke is associated with the development of emphysema in rats. Journal of Nutrition, 133: 2629-2634, 2003.

Baybutt, R.C., Hu., L. & Molteni, A. Vitamin A deficiency injures lung and liver parenchyma and impairs function of rat type II pneumocytes. Journal of Nutrition, 30: 1159-1165, 2000.

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