Pattle Pak-Toe Pun, Ph.D.

Biology

Professor of Biology Emeritus
On Faculty since 1973

Phone: (630)752-5303
Email:

Education

Ph.D. Biology, State University of New York at Buffalo, 1974

M.A. Biology, State University of New York at Buffalo, 1972

M.A. Theology, Wheaton College, 1985

B.S. Chemistry, San Diego State University, 1969

About Pattle Pak-Toe Pun

Pattle Pun’s research, publications and professional experience focus on microbial and molecular genetics, using primarily bacterial systems. He has recently devoted more time to the studies of genomics. He is also interested in the integration of the Christian faith with professions, having the opportunities to address these issues in numerous occasions in the States and abroad. He is actively involved in Sunday School teaching as well as outreach to international students.

Courses Taught

  • BIOL 361 Cellular and Molecular Biology
  • BIOL 364 Microbiology and Immunology
  • BIOL 353 Molecular Genetic
  • BIOL 365 Electron Microscopy
  • BIOL 358 Recombinant DNA
  • BIOL 241 College Biology I
  • BIOL 284 Introduction to Research
  • BIOL 252 Biological Systems
  • BIOL 317x Biomedical Ethics (Bioethics)
  • BIOL 494 The Integrated Biologist
  • BIOL 374 Bioinformatics

Membership in Professional Societies

  • The American Society for Microbiology
  • The American Scientific Affiliation
  • The International Society for Complexity, Information and Design
  • Fellow of the American Scientific AffiliationWheaton College Scholastic Honor Society
  • President of the Wheaton College Scholastic Honor Society, 1987-88

Research

Collaborative research with the Chinese University of Hong Kong Bioinformatics Center and Wheaton College students by Dr. Pattle Pun gather bioinformatics evidence for the functional interpretations of the non-coding sequences of the human genome project.

Papers Published and/or Presented

Selected Publications

"Introduction to Biotechnology Research: The Cloning of the Known Genes in Bacillus subtilis by Student Designed Primers", P.P. Pun, Wheaton College, Wheaton, IL. Poster 25A, Eighteenth Annual Conference for Undergraduate Educators, American Society for Microbiology, BLENDING SCIENCE AND EDUCATION, June 2-5, 2011, Johns Hopkins University Homewood Campus, Baltimore, MD.

Application of the Gene-Ratio Method in the Diagnosis and Prognosis of a Variety of Human Diseases, Nathan Gaines(1,) Christine O’Rourke(1), Pattle Pun(1), Gavin Gordon (2), (1) Biology Department, Wheaton College, Kenilworth Street, Wheaton, IL (60187), (2) Division of Thoracic Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA (02115), Journal of Biology, Biological Systems and Bioinformatics, Volume 3, Issue 1, 2009, p. 1-8.

Pun, Pattle P. 2007. Integration and Confrontation of Contemporary Worldviews: Evolution and Intelligent Design. Perspectives in Science and Christian Faith, (June) 59(2): 102-109.

Abstract 706.21: “Applicability of cDNA and Oligonucleotide Microarray to a Diagnostic Test of Human Disease using Gene Expression Ratios”, Nathan Gaines(1), Ryan Wilke(1), Pattle Pun(1), Gavin Gordon(2), (1)Biology Department, Wheaton College, Wheaton, IL (60187), (2)Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (02115); Experimental Biology 2007: Today’s Research: Tomorrow’s Health. 2007 meeting of the Federation of American Societies for Experimental Biologists (FASEB), Washington, DC, April 28 – May 2, 2007.

Pun, Pattle P. 2006. April 15 (Ephesians 5:17). In Stones of Remembrance 2: Wheaton’s Living Stones, ed. Emily Louise Zimbrick, p 117, Wheaton, IL: Wheaton College.

“Application of a Genomics-Based Diagnostic Test for Human Diseases.” Christine O’Rourke(1), Gavin J. Gordon(2), and Pattle Pun(1). (1)Biology Department, Wheaton College, Wheaton, IL (60187), (2)Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (02115). Abstract in Experimental Biology (EB) 2006 meeting of the Federation of American Societies for Experimental Biologists (FASEB), San Francisco, CA, April 1 – 5, 2006.

"Validation of a Genomics-Based Diagnostic Test for Lung Cancer and Mesothelioma" Brian Pottorf (1), Scott Snyder (1), Pattle Pun (2), Raphael Bueno (1), and Gavin J. Gordon (1). (1) Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (02115); (2) Biology Department, Wheaton College, Wheaton, IL (60187). Experimental Biology (EB) 2005 meeting of the Federation of American Societies for Experimental Biologists (FASEB), San Diego, CA, April 1 – 5, 2005. Abstract 298.4.

"The Three Domains of Life: A Challenge to the concept of the Universal Cellular Ancestor?", P.P.Pun, S. Schuldt, and B. Pun, Progress in Complexity, Information and Design, Vol. 4.2, November, 2005

"The Three Domains of Life: A Challenge to the concept of the Universal Cellular Ancestor?", Abstract presented at the 57th Annual Conference of the American Scientific Affiliation, August, 2002.

Pun, Pattle P. T. , Evolution: Nature and Scripture in Conflict?. 1982. Zondervan. Grand Rapids. MI, USA. Chinese edition by Christian Renewal Ministries, E. Brunswick, NJ, USA. 1984, 1989, 1992, 1994. Web edition, 2002, Interdisciplinary Biblical Research Institute, Hatfield, PA, USA.

Contributor to the book, Reading for Life, edited by Jeff Davis, Tom Martin and Lee Ryken, Xlibris publisher, Random House, 2001, p. 155-157.

"Four taxa protein sequence analyses using protein sequence parsimony (PROTPARS) and neighbor joining (NEIGHBOR) methods suggest sequence assortments into the three domains of Archeae, Bacteria, and Eucaryaas independent lineages", P.P.Pun1, S. Schuldt1, B. Pun1, T. Wood2 and C. Ihm1, 1Wheaton Col. Wheaton, IL and 2Clemson Univ., Clemson, SC, Abstract, 100th General Meeting of the American Society for Microbiology, Los Angeles, CA, May 21-25, 2000.

"Towards an Ethics of the Human Genome Project", Journal of the American Scientific Affiliation. (Perspectives on Science and Christian Faith), September, 1998, p. 164-175.

"The Cloning and Sequencing of the Indoleglycerol Phosphate Synthetase Gene (trpC) of Bacillus megaterium". L.M. Jablonski, P.P.T.Pun, D.S.Hudspeth, D. Stevenson and P.S.Vary (manuscript in revision).

"Genetic Engineering and the Future of Man". Christian Arts Press, Taipei, Dec. 1995 (in Chinese). Second printing, Sep. 1997.

"Critical nucleotides in the Interaction of a LysR-type Regulator with Its Target Promoter Sequence: catBC promoter Activation by CatR". M. R. Parsek, R. Ye, P. Pun and A. M. Chakrabarty, Journal of Biological Chemistry, Vol. 269 (15), April 15, 1994, p. 11279-11284.