The Museum, located on the first floor of the main section, houses interesting displays on the history of evangelism, highlights of the Billy Graham Evangelistic Association, and a graphic presentation of the gospel.
On the second floor is the Wheaton College Graduate School. The Billy Graham Center Archives and Buswell Library’s department of College Archives and Special Collections are found on the third floor, The Evangelism and Missions Collection is one of over two hundred special collections that range from the papers of Malcolm Muggeridge and Frederick Buechner to memorabilia highlighting the College's rich history. The Evangelism and Missions Collection and the Billy Graham Center Archives are devoted to the history of world missions and evangelism.
The fifth floor is home to the department of Biblical and Theological Studies.
The 500-seat Barrows Auditorium in the east wing is a popular venue for conferences, recitals, lectures, and other events.
The west wing houses the College's Communication and Psychology departments and the Advancement offices including Media Relations. In the basement is the Academic and Media Resources department, a full-production facility for audio, video, and radio production, and home of Wheaton College's radio station, WETN, and cable station CH72 WETN.